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  • ADD, ADHD - Richardson AJ, Puri BK. A randomized double-blind, placebo-controlled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specific learning difficulties. Prog Neuropsychopharmacol Biol Psychiatry 2002;26:233–9.
  • Allergies Arm JP, Horton CE, Eiser NM, et al. The effects of dietary supplementation with fish oil on asthmatic responses to antigen. J Allergy Clin Immunol 1988;81:183 [abstract #57].
  • Alzheimer’s British Medical Journal (2002;325:932–3).  
  • Arrhythmia (hear beat messed up)- Nair SSD, Leitch JW, Falconer J, Garg ML. Prevention of cardiac arrhythmia by dietary (n-3) polyunsaturated fatty acids and their mechanism of action. J Nutr 1997;127:383-93.   
  • Atherosclerosis (Plaque build up that hardens and blockss the arteries) von Schacky C, Angerer P, Kothny W, et al. The effect of dietary omega-3 fatty acids on coronary atherosclerosis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1999;130:554-62.
  • Arthritis Kremer JM, Lawrence DA, Petrillow GF, et al. Effects of highdose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs. Arthritis Rheum 1995;38:1107-14.
  • Asthma - Broughton KS, Johnson CS, Pace BK, et al. Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production. Am J Clin Nutr 1997;65:1011–7.
  • Autoimmune disorders (e.g. Lupus and nephropathy) - Donadio JV Jr, Bergstrahl EJ, Offord KP, et al. A controlled trial of fish oil in IgA nephropathy. N Engl J Med 1994;331:1194-9.
  • Blood Pressure Blood pressure response to fish oil supplementation: metaregression analysis of randomized trials. Journal of Hypertension, 2002, Vol 20, Iss 8, pp 1493-1499. JM Geleijnse, EJ Giltay, DE Grobbee, ART Donders, FJ Kok. Geleijnse JM, Univ Wageningen & Res Ctr, Div Human Nutr & Epidemiol, POB 8129, NL-6700 EV Wageningen, NETHERLANDS
  • Bipolar -  Bipolar - Stoll AL, Severus WE, Freeman MP, et al. Omega 3 fatty acids in bipolar disorder. A preliminary double-blind, placebo-controlled trial. Arch Gen Psychiatr 1999;56:407–12
  • Breast Feeding Support - Breast Feeding Support -  Jorgensen MH, Hernell O, Hughes E, Michaelsen KF. Is there a relation between docosahexaenoic acid concentration in mothers’ milk and visual development in term infants? J Pediatr Gastroenterol Nutr 2001;32:293–6.
  • Cancers of the breast, colon and prostate - Zhu ZR, Mannisto JAS, Pietinene P, et al. Fatty acid composition of breast adipose tissue in breast cancer patients and patients with benign breast disease. Nutr Cancer 1995;24:151-60.
  • Chronic obstructive pulmonary disease (COPD) Shahar E, Folsom AR, Melnick SL, et al. Dietary n-3 polyunsaturated fatty acids and smoking-related chronic obstructive pulmonary disease. Atherosclerosis Risk in Communities Study Investigators. N Engl J Med 1994;331:228-33.
  • Crohn disease  Mate J, Castanos R, Garcia-Samaniego J, Pajares JM. Does dietary fish oil maintain the remission of Crohn’s disease: a case control study. Gastroenterology 1991;100:A228 [abstract].
  • Cystic fibrosis - Lawrence R, Sorrell T. Eicosapentaenoic acid in cystic fibrosis: evidence of a pathogenic role for leukotriene B4. Lancet 1993;342:465–9.
  • Depression - Depression - Puri BK, Counsell SJ, Richardson AJ, Horrobin DF. Eicosapentaenoic acid in treatment-resistant depression. Arch Gen Psychiatry 2002;59:91–92 [Letter].
  • Diabetes - Malasanos TH, Stacpoole PW. Biological effects of omega-3 fatty acids in diabetes mellitus. Diabetes Care 1991;14:1160–79.
  • Endometriosis - Batchelder HJ, Hudson T, Lewin A, et al. Therapeutic approaches to endometriosis. The Protocol Journal of Botanical Medicine 1996;Spring:25–60
  • Energy - Puri BK. The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids 2004;70:399–401.
  • Eczema - Bjørnboe A, Søyland E, Bjørnboe GE, et al. Effect of n-3 fatty acid supplement to patients with atopic dermatitis. J Intern Med Suppl 1989;225:233–6.
  • Epilepsy - Schlanger S, Shinitzky M, Yam D. Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients. Epilepsia 2002;43:103–104.
  • Glaucoma - McGuire R. Fish oil cuts lower ocular pressure. Med Tribune 1991;Sept 19:25.
  • Immune problems - Alexander JW. Immunonutrition: the role of omega-3 fatty acids.Nutr 1998;14:627-33.
  • Infections - Gerster H. The use of n-3 PUFAs (fish oil) in enteral nutrition. Int J Vitam Nutr Res 1995;65:3–20 [review].
  • Intermittent claudication - Carrero JJ, Lopez-Huertas E, Salmeron LM, et al. Daily supplementation with (n-3) PUFAs, oleic acid, folic acid, and vitamins B-6 and E increases pain-free walking distance and improves risk factors in men with peripheral vascular disease. J Nutr 2005;135:1393–9.
  • Joint Pain, back, neck, hips, elbow, knee etc (Kremer, Lipids 31 Suppl: S243-247, 1996) (Geusens, Arthiritis Rheum. 37:824-829, 1994) (Kremer, Arthritis Rheum. 38:1107-1114, 1995)
    (Uauy-Dagach, R et al, Nutr Review. 54:S102-S108, 1996) (IBID Kremer, 1995)
  • Kidney diseases - Peck LW. Essential fatty acid deficiency in renal failure: can supplements really help? J Am Diet Assoc 1997;97:5150-3.
  • Lupus - Walton AJE, Snaith ML, Locniskar M, et al. Dietary fish oil and the severity of symptoms in patients with systemic lupus erythematosus. Ann Rheum Dis 1991;50:463–6.
  • Manic Depression - Puri BK, Counsell SJ, Richardson AJ, Horrobin DF. Eicosapentaenoic acid in treatment-resistant depression. Arch Gen Psychiatry 2002;59:91–92 [Letter].
  • Migraine headaches - McCarren T, Hitzemann R, Allen C, et al. Amelioration of severe migraine by fish oil (omega-3) fatty acids. Am J Clin Nutr 1985;41:874 [abstract].
  • Mind Performance Kalmijn S, et al. Dietary intake of fatty acids and fish in rlation to connitive performance at middle age.  Neurology,  2004 Jan 27;62(2):275-80
  • Multiple sclerosis - Nordvik I, Myhr KM, Nyland H, Bjerve KS. Effect of dietary advice and n-3 supplementation in newly diagnosed MS patients. Acta Neurol Scand 2000;102:143–9.
  • Osteoporosis -Van Papendorp DH, Coetzer H, Kruger MC. Biochemical profile of osteoporotic patients on essential fatty acid supplementation. Nutr Res 1995;15:325–34.
  • Painful menstruation (dysmenorrheal) Harel Z, Biro FM, Kottenhahn RK, Rosenthal SL. Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents. Am J Obstet Gynecol 1996;174:1335–8.
  • Phenylketonuria - Agostoni C, Riva E, Biasucci G, et al. The effects of n-3 and n-6 polyunsaturated fatty acids on plasma lipids and fatty acids of treated phenylketonuric children. Prostaglandins Leukot Essent Fatty Acids 1995;53:401–4.
  • Photosensitivity -Rhodes LE, Durham BH, Fraser WD, Friedmann PS. Dietary fish oil reduces basal and ultraviolet B-generated PGE2 levels in skin and increases the threshold to provocation of polymorphic light eruption. J Invest Dermatol 1995;105:532–5.
  • Pregnancy and postpartum support - Olsen SF, Secher NJ, Tabor A, et al. Randomised clinical trials of fish oil supplementation in high risk pregnancies. Fish Oil Trials In Pregnancy (FOTIP) Team. Brit J Obstet Gynecol 2000;107:382–95.
  • Psoriasis - Bittiner SB, Tucker WFG, Cartwright I, Bleehen SS. A double-blind, randomised, placebo-controlled trial of fish oil in psoriasis. Lancet 1988;i:378–80.
  • Raynaud’s disease - Raynaud’s disease - . DiGiacoma RA, Kremer JM, Shah DM. Fish-oil dietary supplementation in patients with Raynaud’s phenomenon: a double-blind, controlled, prospective study. Am J Med 1989;86:158-64.
  • Schizophrenia Laugharne JDE, Mellor JE, Peet M. Fatty acids and schizophrenia.Lipids 1996;31:S163-5.
  • Skin look and feel better – Ziboh VA, et al. Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of anti-inflammatory and antiproliferative metabolites.  Am J Clin Nurt. 2000 Jan;71 (1Suppl):361S-6S
  • Sickle cell anemia -Muskiet FA, Muskiet FD, Meiborg G, Schermer JG. Supplementation of patients with homozygous sickle cell disease with zinc, alpha-tocopherol, vitamin C, soybean oil, and fish oil. Am J Clin Nutr 1991;54:736–44.
  • Stress and Inflamation Problems - Maes M, Christophe A, Bosmans E, et al. In humans, serum polyunsaturated fatty acid levels predict the response of proinflammatory cytokines to psychological stress. Biol Psychiatry 2000;47:910-20.
  • Ulcerative colitis - Ulcerative colitis - Stenson WF, Cort D, Rodgers J, et al. Dietary supplementation with fish oil in ulcerative colitis. Ann Intern Med 1992;116:609–14.

Our bodies operate best when we give it the foods and nutritional support they provide.  But if you already have a medical condition please realize these references are for educational purposes only and are not to used as a substitute for a person getting and following medical advice from a M.D.


  		   
 
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